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Treatment Schedule: Injections are typically administered three times per week, with at least one day in between each injection to ensure optimal results
Administration: Subcutaneous injection (abdomen, thighs, or upper arms) Typical dosing range: 2-5 mg per week, often split into two injections of 1,250-2,500 mcg during the loading phase Cycle length: Loading phase of 4-6 weeks at 4-8 mg/week, followed by a maintenance phase of 4-8 weeks at 2-2.5 mg/week
There is no trial data establishing an optimal duration for MOTS-c, so that range comes from clinical practice and pharmacologic reasoning rather than from published head-to-head comparisons
It is frequently indicated for fatigue, numbness, and neurological discomfort due to B12 deficiency
Ann Emerg.Med 2007;49(6):794-801, 801
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